Animal Models
Our expertise in preclinical models ensures the selection, adaptation, and development of the most suitable research models to support drug discovery and development. We provide a comprehensive portfolio of models, toxicology studies, and advanced AI-driven analysis to optimize preclinical research outcomes.
Large Portfolio of Preclinical Models
Access to a wide range of validated preclinical models for various therapeutic areas.
TOX (In-Vivo and In-Vitro, GLP or Non-GLP)
Conducting toxicology studies under Good Laboratory Practice (GLP) or non-GLP conditions to assess safety profiles.
ADME & PK Studies and AI Modelling
Evaluating Absorption, Distribution, Metabolism, and Excretion (ADME) along with Pharmacokinetics (PK) using advanced AI-driven modeling.
Models Transfer from Academia
Facilitating the transfer and implementation of innovative models from academic research to industry applications.
Adapting & Developing New Models
Customizing and innovating preclinical models to meet specific research needs and emerging scientific challenges.
Our expertise covers a wide range of medical indications and animal species
Cellular Functional Assays
- Cell proliferation/viability: MTT/MTS
- Cytotoxicity : LDH release assay
- Apoptosis :FACS (Annexin V & PI),
- Caspase 3/7 . Cell Cycle: FACS
- Tox system for the prediction of
- drug‐induced liver injury risk ( using
- human serum)
- Array-based multiplex ELISA system
Ophthalmology
- Conjunctivitis Induced by Staphylococcal
- Retina degeneration Sodium Iodate-induced
- Glaucoma laser-induced
- Glaucoma Silicon oil induced
- Retinal damage Hyperglycemia-induced
- Retinal damage -Light-induced (fish, rodent)
- Age macula degeneration (AMD)
- Two-stage laser induced subretinal fibrosis
Metabolic disorders
- Obesity diet-induced (DIO)
- Diabetes, Type I, Streptozotocin-Induced
- Diabetes, Type II, Diet-Induced
- NASH, MCD Diet-Induced
- NASH, CDAHFD Diet-Induced
- Sarcopenia in aged rodent
- Acute dyslipidemia Triton-induced
Fibrosis
- Skin Fibrosis Bleomycin-induced
- Scleroderma Bleomycin-induced
- Pulmonary fibrosis Bleomycin-induced
- kidney fibrosis induced by:
- Folic acid (FA) (rodent)
- Unilateral ureteral obstruction (UUO)
- Kidney injury I/R Induced
- Liver fibrosis induced by:
- Hight fat diet
- Different type of diets
- Carbon tetrachloride (CCl4)
- Alcohol-induced steatohepatitis
Pain and inflammation
- Pain Formalin-Induced
- Pain Carrageenan-Induced
- Pain CFA induced
- Pain Post-operative
- Osteoarthritis MIA-induced
- Arthritis Adjuvant-Induced
- Arthritis collagen-Induced
- Spared nerve injury (SNI)
- Chronic constriction injury (CCI)
- Pain Chemotherapy-Induced
- DSS-induced IBD
- IMQ-induced psoriasis
- Skin Inflammation IL-23 induced
- Vulvodynia CFA or surgery-induced
Oncology
Xenograft Models
- Pancreatic model with Mia-Paca-2, Bx-PC3
- Kidney model with 786-O
- Disseminated model with Raji
- Breast (mammary fat pad) model with
- MDA-MB-231
- Lung Metastatic Model with A-549
- In-vivo model in chick embryo
Cartilage Tissue Repair
Intervertebral disc repair
Intra-articular particulate injection
Meniscectomy transection
Osteochondral defect
Respiratory
- Bleomycin (Blm)-induced Pulmonary Fibrosis
- Bleomycin (Blm)-induced Pulmonary Fibrosis
- Pulmonary Arterial Hypertension (PAH) Model
- OVA Induced Asthma Model
- LPS Induced Acute Inflammation Model
- Citric acid-induced cough in conscious guinea
- pigs
Dental surgery
Tooth extraction
Bone regeneration
Dental implants
Otology
- Aging-induced hearing loss (SAMP8)
- Hearing loss cisplatin-induced
- Hearing loss noise-induced
- Cochlear implant model
- In-vitro model
Other models
- Duchenne Muscular Dystrophy (drosophila)
- Experimental autoimmune neuritis (EAN) 6-
- OHDA rat model of Parkinson disease
- Traumatic brain injury (rodent)
- Sepsis LPS-induced